Dlk2（Delta-like2homolog）属EGF样跨膜蛋白，与同家族成员Dlk1（Delta-like1homolog）高度同源。现有研究发现Dlk1在包括脂肪生成和肌肉生成在内的多个发育过程中发挥重要作用。但是目前对Dlk2的研究还主要限于脂肪生成过程，迄今为止尚未见Dlk2在骨骼肌生成方面的报道。 本研究首次考察了Dlk2在骨骼肌发育中的作用。首先，通过检测不同发育时期的鸡骨骼肌组织中cDLK2的表达水平，我们发现其在胚胎骨骼肌发育早期较高，而随发育的进行逐渐降低并在出壳后维持较低水平，说明Dlk2可能在胚胎骨骼肌早期发育中发挥作用。接着，我们利用小鼠成肌细胞系C2C12模型发现...The protein Dlk2 (Delta-like 2 homolog) belongs to the EGF-like family of membrane proteins. Accumulating evidence suggests that Dlk1, highly homologous to Dlk2, is involved in several differentiation processes, including adipogenesis and myogenesis. However, limited previous studies on Dlk2 are almost directed to adipogenesis, and its function in myogenesis has not been reported. The present s...学位：理学博士院系专业：生命科学学院_细胞生物学学号：2162010015392
