先以壳聚糖(CS)用戊二醛(gA)交联为刚性网络,后将聚乙二醇马来酸酐双酯(MAH PEgMAH)与n-乙烯基吡咯烷酮(VP)的共聚物交联成柔性网络,合成了一种高强度且具有P H值、电场敏感性的智能型双网络水凝胶。利用红外光谱、扫描电镜表征了凝胶的化学结构和内部形态;X射线衍射研究了凝胶的结晶性能;研究了凝胶的力学性能及其影响因素,探讨了凝胶的P H值、电场敏感性能。研究结果表明,当CS含量为20%,gA用量为0.2 g gA/g CS,PEg相对分子质量为1000,bIS用量为0.5%时,所制备凝胶的压缩强度可达9.3 MPA。随着PEg相对分子质量的增加,凝胶的P H值敏感性增强;随CS交联度的增加,凝胶的最大弯曲角和电场敏感性先增加后降低。A kind of high strength intelligent double network(DN) hydrogel was synthesized by two-step cross linked method.Firstly chitosan(CS) was cross linked with glutaraldehyde(GA),secondly polyethylene glycol and maleic anhydride esterified products(mah PEGmah) and N- vinylpyrrolidone(VP) copolymers were cross linked with N,N'-methylene double acrylamide(BIS).The DN hydrogel has good p H and electric field sensitivity.The structure of resultant hydrogel was characterized by Fourier transform infrared(FT-IR) spectroscopy,scanning electron microscopy(SEM),crystallization properties of composite hydrogels were investigated by X-ray diffraction(XRD).It's found that when the CS content is 20%,the GA used content is 0.2 g GA/g CS,the molecular weight of PEG is 1000,and the BIS used content is 0.5%,the hydrogel strength of the compression rises up to 9.3 MPa.With the molecular weight of PEG increasing,the p H stim-response sensitivity of hydrogel is improved.With the degree of crosslinking increasing,the maximum bending angle of the gel and the electric field sensitivity of the hydrogel are decreased
