Experimental Study of the Effect of ulinastatin combined with xuebijing injection on the treatment of intestinal mucosa injury in rats with seawater immersion after open abdominal injury
目的：研究乌司他丁联合血必净对海水浸泡腹腔开放伤大鼠肠屏障功能的保护作用及机制。 方法：104只雄性Wistar大鼠随机分为5组:对照组(A组),海水浸泡腹腔开放伤生理盐水治疗组(B组),乌司他丁处理组(C组),血必净处理组(D组),乌司他丁联合血必净处理组(E组)；B、C、D、E组又随机等分为1h、3h、6h3个亚组，每组8只。各组分别在术后第1、3、6h采集血液、小肠组织标本。采用酶联免疫分析法检测血浆肿瘤坏死因子α(tumornecrosisfactor-α,TNF-α)、白介素6(interleukin-6,IL-6)、内毒素(endotoxin,ET)含量,分光光度法检测血浆中二胺...Objectives：To investigate the protective effects of ulinastatin combined with xuebijing injection on the treatment of intestinal mucosa injury in rats with seawater immersion after open abdominal injury. Methods：A total of 104 male Wistar rats were randomly divided into 5 groups that consisted of a normal control group, a normal saline treated group, a ulinastatin treated group, a xuebijing inje...学位：医学硕士院系专业：医学院_外科学学号：2452011115340
