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A preliminary study on the major histocompatibility complex (MHC) class II B genes in 13 species of ardeid birds (Aves:Ardeidae)

Abstract

主要组织相容性复合体(Majorhistocompatibilitycomplex,MHC)基因是脊椎动物体内与免疫功能密切相关的一个的基因家族,其基因编码的蛋白在调节免疫系统识别自身和异物之间起着重要的作用。MHC变异反映种群内、种群间与进化相关的适应性过程,适合于研究进化生态学和保护学方面的一些问题。 本文鉴定了分布于中国境内鹭科鸟类(ardeidae)的两个经典MHCII类基因(DAB1、DAB2),并设计通用引物分析了鹭科鸟类7属13种的MHCIIDAB基因,特别是包含假定的肽链结合区(peptide–bindingregion,PBS)的第二外显子的序列变异情况,初步研究不同物种序...The major histocompatibility complex (MHC) of vertebrates is a highly polymorphic genomic family which is closely related to immunity respond and playing an important role in the regulation of immune system to recognize external pathogen. The variability of MHC gene reflects evolutionary adaptive processes within and between populations and become a suitable tool to investigate a wide range of ope...学位:理学博士院系专业:生命科学学院_动物学学号:2162007015381

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