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Effects of oleoyethanolamide on the develpment of atherosclerosis

Abstract

研究背景:动脉粥样硬化(AS)是现在世界范围内最普遍存在的严重威胁人类健康的心血管疾病之一。随着肥胖和糖尿病患病人口比例的不断上升,由动脉粥样硬化引起的心血管疾病如冠心病(CHD)等已经成为全球人口死亡的主要原因。冠状动脉的粥样硬化的情况也已经成为临床上考察心血管系统是否健康的重要检测项目。因此,寻找动脉粥样硬化药物的研究成为国内外药物研究的热点。 很多学者认为,动脉粥样硬化的发展进程从童年就已经开始了,它缓慢且不易察觉的发展,直到我们步入中年时才表现出症状。肥胖、高血压、高脂血症和糖尿病等代谢紊乱疾病是动脉粥样硬化诱发的主要因素。而动脉粥样硬化顽固斑块一旦形成,则很难将其清除根治。所以,对...Background: Atherosclerosis(AS) is one of the most principal causes of cardiovascular diseases which seriously threatens the public health throughout the world. Cardiovascular diseases are expected to be the main cause of death globally for the recent years owing to the rising incidence of obesity and diabetes in the world. Coronary artery atherosclerosis has been a major focus for clinical in...学位:理学硕士院系专业:医学院基础医学系_药理学学号:2452009115301

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