摘要超氧化物歧化酶(Superoxidedismutase,SOD)是一种重要的氧自由基清除剂,它催化超氧阴离子自由基(superoxideradical,O2-)的歧化反应。O2-被认为对各种生物大分子及其它细胞组分具有严重的损伤作用,SOD能预防和治疗由超氧阴离子自由基引起的多种疾病如家族性肌萎缩性侧索硬化(FALS)等。在临床上,已用于一些炎症、肿瘤、皮肤病、心血管病等疾病的治疗,用于延缓衰老。在国外,已有含SOD化妆品制剂、抗辐射SOD胶囊、治疗局部缺血症SOD制剂等的专利生产。美国、日本及西欧一些国家早已开发重组人SOD药物,有的已经进入Ⅱ期和Ⅲ期临床研究。因而SOD是一种很有前途的...Abstract The Superoxide dismutase is an important oxygen free radical scavenger which catalyzes the superoxide anion radical disproportionation reaction. It was considered that O2- has serious damage to biological macromolecule and other cell components. SOD can prevent and treat the many kinds of diseases which causes by the superoxide radicals (such as familial amyotrophic lateral sclerosis, FAL...学位:理学硕士院系专业:生命科学学院生物学系_水生生物学学号:20042601