The aim of this thesis was
1) to describe the similarities and differences between recommendations for pharmacotherapy of low back pain (LBP) from recent clinical practice guidelines;
2) to investigate if the results and inferences from the Paracetamol for Acute Low Back Pain (PACE) trial could be reproduced;
3) to assess the efficacy of paracetamol for acute non-specific LBP in participants of the PACE trial who complied with the treatment regimen; and
4) to investigate if there is an association between reporting adverse events (AEs) and the outcomes of acute LBP
