IL-13 inhibition by tralokinumab reduces ICOS+ innate lymphoid cells in the skin lesion of atopic dermatitis_Fig.S1

Abstract

(A) The representative immunohistochemical analysis of IL-13Rα1 expression by multiplex fluorescent staining for ICOS+ ILCs (left bottom bar: 10 µm)  (B) Lin+ICOS+ cells (mainly activated T cells) and Lin+ICOS- cells (bulk population of differentiated cells). Lin+ICOS+ cells are indicated by white arrowheads, while Lin+ICOS- cells are indicated by red arrowheads (left bottom bar: 10 µm). Each channel of multiplex fluorescent staining is shown with merged pictures. 400-fold magnification was used to obtain original pictures.</p