Presented online on November 19, 2021 at the Advancing Ethical Research (AER) conference.NIH has announced a new Data Management and Sharing Policy, which takes effect for grants submitted on or after January 25, 2023. This policy will impact NIH-funded researchers, with implications for IRBs, research compliance associates, and other stakeholders. NIH's "expectations for robust data management and sharing practices [and] a future in which data sharing is a community norm" will require focused outreach, education, and development of tools during the coming year to prepare successful 2023 grant applications. In this presentation, we will outline NIH's expectations, explore specific challenges and opportunities afforded by the new policy, and offer suggestions for how academic medical centers can develop resources and workflows to support researchers and comply with the new policy.http://deepblue.lib.umich.edu/bitstream/2027.42/171055/1/SessionF9_PaineSamuel_AER21_20211025.pptxhttp://deepblue.lib.umich.edu/bitstream/2027.42/171055/5/SessionF9_PaineSamuel_AER21.pdfSEL