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Schizophrenia polygenic risk score and long-term success in the labour market : A cohort study
Authors
Petri Böckerman
Christian Hakulinen
+5 more
Jaana T. Kari
Terho Lehtimäki
Jaakko Pehkonen
Olli T. Raitakari
Jutta Viinikainen
Publication date
1 July 2022
Publisher
Doi
Cite
Abstract
Publisher Copyright: © 2022 The AuthorsEmployment is rare among people with a schizophrenia diagnosis. Meanwhile, a genetic liability for schizophrenia may hinder labour market performance. We studied how the polygenic risk score (PGS) for schizophrenia related to education and labour market outcomes. We found that a higher PGS was linked to lower educational levels and weaker labour market outcomes as well as a higher likelihood of receiving social income transfers, particularly among men. Assuming that the link is causal, our results indicate that individuals with schizophrenia or schizophrenia-related traits have a weakened ability to fully participate in the labour market, potentially reinforcing social exclusion.Peer reviewe
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Helsingin yliopiston digitaalinen arkisto
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oai:helda.helsinki.fi:10138/35...
Last time updated on 21/02/2023
Trepo - Institutional Repository of Tampere University
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oai:trepo.tuni.fi:10024/141665
Last time updated on 22/08/2022