With the growing emphasis on scientific integrity as a way to curb research misconduct, the “moral obligation to act” when a researcher observes a breach of integrity is becoming stronger. However, it takes a lot of courage to blow the whistle as it can have an enormous impact on the whistleblower’s career and personal well-being – and that of colleagues and researchers associated with the perpetrator. Therefore, it is important to be cognizant of the stressful process that accompanies the act of whistleblowing, to provide clear and accessible procedures to report misconduct, and to support whistleblowers throughout the process. Furthermore, it is essential that appropriate whistleblower protection measures are in place and enforced. Based on our review, we argue that an obligation to report scientific misconduct would currently do more harm than good
