U cilju utvrđivanja svrsishodnosti rutinske patohistološke analize kiretmana nakon evakuacije uterusa poradi poremećene rane trudnoće proveli smo retrospektivno istraživanje kojim su obuhvaćene sve pacijentice koje su, tijekom jednogodišnjeg razdoblja, nakon dijagnoze poremećene trudnoće u prvom tromjesečju, imale evakuaciju uterusa kiretažom. Od ukupno 335 bolesnica tijekom godine dana, 312 ih je imalo nalaz patohistološke analize te su uključene u konačnu analizu. U 272 (87,2 %) histopatološkom analizom potvrđeno je tkivo trofoblasta, dok u ostalih 40 (12,8 %) tkiva trofoblasta nije nađeno unatoč uputnoj dijagnozi. U 10 (3,2 %) ispitanica histopatološkom analizom postavljena je dijagnoza gestacijske trofoblastične bolesti na koju se nije sumnjalo prije evakuacije uterusa. Kod jedne je ispitanice (0,3 %) sumnja na gestacijsku trofoblastičnu bolest isključena histopatološkom analizom. Zaključno, rutinska patohistološka analiza kiretmana nakon evakuacije uterusa indicirane poremećenom ranom trudnoćom potencijalno utječe na daljnji tijek liječenja u 16,3 % ispitanica te je unatoč troškovima opravdana u rutinskoj kliničkoj praksi.The aim was to determine usefulness of routine pathologic evaluation of uterine content after uterine evacuation following the diagnosis of abnormal early pregnancy. This retrospective descriptive study performed during a one-year period included all patients diagnosed with abnormal early pregnancy clinically or by ultrasound in the fi rst trimester. All patients had uterine evacuation. During the study period, 335 women were diagnosed with abnormal early pregnancy and referred for uterine evacuation. Pathology results were available for 312 women included in the analysis. In 272 (87.2%) women, trophoblast tissue was found on examination and therefore intrauterine pregnancy was confi rmed. In the remaining 40 patients,
trophoblast was not found. In 10 (3.2%) patients, gestational trophoblastic disease was diagnosed, not being suspected on pre-evacuation assessment. In one patient, suspected molar pregnancy was excluded by pathology evaluation. Based on 51/312 (16.3 %) patients where pathology examination of uterine content infl uenced further management and treatment, we believe that routine pathology examination of uterine content after uterine evacuation in the fi rst trimester following abnormal early pregnancy is justifi able in clinical practice
