Neuroleptic Malignant Syndrome is one of the life threatening complications of antipsychotic psychotropic medication. We here
report a case of a 39 years old male who has had a diagnosis of paranoid schizophrenia since the age of 18 .He had been on
antipsychotic therapy since then. He was stable on a combination of antipsychotics. He had mild hyper-salivation for a long time but
was not very concerned about it. He requested and was prescribed Hyoscine Hydrobromide 300 mcg BD for hyper-salivation. There
was no other medication change. After 5 days of starting Kwells, the patient presented with Neuroleptic Malignant syndrome. One
has to watch for NMS while starting Hyoscine Hydrbromide for someone on antispychotics