Sestre Milosrdnice University hospital and Institute of Clinical Medical Research
Abstract
In the present study, the impact of the potential perinatal epidemiological factors on preeclampsia development was assessed. This clinical study included 55 pregnant women with preeclampsia and control group of 50 healthy pregnant women. Positive family history of cardiovascular disease, diabetes mellitus or thromboembolic disease was recorded in 50% of women with preeclampsia versus 28% of control group women. Positive personal history of this disease was recorded in 15% of women with preeclampsia, whereas all control group women had negative personal history of preeclampsia. Dietary habits, i.e. the intake of meat and meat products, fruit and vegetables, coffee and alcohol drinks were similar in the two groups, without statistically significant differences. The women with preeclampsia and control women reported comparable habits; there was no difference in the consumption of meat, fruit, vegetables, coffee and alcohol, smoking, use of folate and oral hormonal contraception before pregnancy, or in physical activity as the potential risk factors for preeclampsia in current pregnancy. However, personal and family history of vascular disease proved to be significant risk factors for the occurrence of preeclampsia, emphasizing the need of lifestyle and dietary modifications with healthy dietary habits, while avoiding adverse habits in pregnancy.U ovom istraživanju ispitan je utjecaj potencijalnih perinatalnih epidemioloških čimbenika na razvoj preeklampsije. U kliničko istraživanje je bilo uključeno 55 trudnica s preeklampsijom i kontrolna skupina od 50 zdravih trudnica. Pozitivna obiteljska anamneza kardiovaskularnih bolesti, šećerne bolesti ili tromboembolija zabilježena je u 50% žena s preeklampsijom u odnosu na 28% u kontrolnoj skupini trudnica. Pozitivna anamneza prethodne preeklampsije zabilježena je u 15% žena u skupini s aktualnom preeklampsijom, dok su sve žene kontrolne skupine imale negativnu anamnezu preeklampsije. Prehrambene navike, odnosno uzimanje mesa i mesnih proizvoda, voća i povrća, kave i alkoholnih pića bile su slične u objema skupinama, bez statistički značajne razlike, kao i primjena oralne hormonske kontracepcije i fizičke aktivnosti prije trudnoće. Međutim, osobna i obiteljska anamneza krvožilnih bolesti pokazale su se značajnim čimbenicima rizika za pojavu preeklampsije, naglašavajući potrebu promjene načina života uz zdrave prehrambene navike i izbjegavanje štetnih navika u trudnoći
