Metastastatic Lesion to the Mandible: The Use of Cytogenetics

Abstract

Postaviti dijagnozu metastatske lezije mandibule velik je izazov, a temelj se nalazi poglavito u histopatologiji. Rijetkima se smatraju udaljene metastaze adenokarcinoma bazalnih stanica (AKBS) u mandibuli iz tumora žlijezda slinovnica. Prijavljen je slučaj mandibularne metastaze AKBS-a iz parotidne žlijezde. Opisana je primjena citogenetike u postavljanju dijagnoze. Citogenetska se analiza može koristiti i kao dodatni postupak u dijagnosticiranju metastaza i preporučuje se kod suspektne metastatske lezije čeljusti.The diagnosis of metastatic lesion to the jaws is difficult, challenging and is based mainly on histopathology. Distant metastasis of basal cell adenocarcinoma (BCAC) to the mandible from salivary gland tumor is considered rare. A case of mandibular metastasis from parotid BCAC is reported. The use of cytogenetics in the diagnostic work-up is described. Cytogenetic analysis may be used as an additional tool for diagnosis of metastases and is recommended when a metastatic jaw lesion is suspected

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