Malnutrition commonly occurs in patients with cancer. This situation can be associated with increased morbidity and mortality.The etiology is not clearly understood but decreased energy intake and increased energy expenditure may be involved. Weaimed to investigate the energy metabolic status including energy expenditure in patients with various cancers. The clinicalfeatures and energy metabolic status measured by indirect calorimetry of 74 patients with cancer (50 men and 24 women;mean age, 64.7 years) were obtained from the medical records. Hypermetabolism was more common and REE/kg (resting energyexpenditure / kg body weight) seems to be more reliable in estimating the true energy expenditure than %REE (measuredREE / predicted REE). The REE/kg and VO2 /kg (oxygen consumption per minute / kg body weight) varied among cancertypes, i.e., they were significantly higher in gastric cancer than in hepatocellular carcinoma. Moreover, REE/kg and VO2/kg wassignificantly higher in cancer stage IV than in stage I, or stages I and II. Patients with or at risk for malnutrition should receiveappropriate nutritional support, which has to be personalized according to tumor site, tumor stage, and the nutritional statusof the patient. This nutritional support should improve not only the patients\u27 quality of life but also their survival
