This article studies the effects of inflation targeting (IT) on relative price variability (RPV) using a data set of twenty countries comprising both targeters and nontargeters. We find that a decline in mean inflation after IT adoption is not necessarily associated with a similar fall in RPV and that what matters most for the structural changes in RPV is the initial inflation regime prior to the adoption of IT rather than IT adoption itself. IT adoption impacts the shape of the underlying relationship between inflation and RPV in countries with initially high inflation rates, moving it from monotonie to the U-shaped profile observed consistently for countries with low-inflation regimes. The minimum point of this U-shaped curve is indicative of the public\u27s expectations of inflation and is very close to the announced target for inflation in most of the countries we study