Cancer, the group of diseases, is characterized by an abnormal cell growth and function, thus the complications in physiological homeostasis. Although, not all tumors are cancerous, but after a certain time/biological events they may turn into cancer. That means, it is always a risk to continue with any type of tumor. Over 100 cancers are affecting human are detected till date. Treatments belong to the types and stages of cancers along with the areas (physiological). However, there is no single cancer therapy, which is free from side effects. Additionally, complications in cellular targeting and therapy-induced second cancer are also evident. Combination treatments are also used in some cases, despite the possibility of immunosuppression and a bundle of unavoidable events. Otherwise, cancer treatment in advanced stages and metastasize are yet being considered. Therefore, scientists are always in search for a new and effective mode of cancer treatment, so that they may ensure less or even no side effects with a promising survival rate. In fact, the economy, safety, and effectiveness are the deemed query of both the patients and physicians. Among the others, the markers coming from the changed cell membrane of a cancerous cell may be good sources to ligand targeting, as these are the basic differentiating matter between a normal and cancer cell. In this hypothesis, the membrane marker sensory strategy is going to be introduced theoretically for the first time may be an alternative and effective mode of cancer treatment
