Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu"
Abstract
Odontology, Periodontology and Oral Pathology chair, Faculty of Stomatology, Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova, Ziua internațională a științei pentru pace și dezvoltareINTRODUCTION. The white lesions of the oral mucosa have a wide range of
clinical manifestations with different etiology and varied
prognosis, from benign conditions to dysplastic or
carcinomatous lesions. Besides the fact that some specific
classical characteristics are known that allow the
differentiation of lesions, there are a number of other
similar manifestations that complicate the determination of
the disease, so the diagnosis establishment represent a
primary direction in their management. PURPOSE. Presentation of known aspects, but also the continuous
development of terms and systems with a clinical value of
white lesions, as well as information on how these terms
should be used in an international consensus. RESULTS. Of the total number of patients included in the study, 4
patients (28.6%) were diagnosed with oral leukoplakia (2
patients - verrucous form, 1 - flat form, 1 - erosive form), 5
(35.7%) – oral lichen planus, 3 (21.4%) - oral candidiasis,
2 (14.3%) - chemical lesion of the oral mucosa.
During the histopathological examination signs of
hyperkeratosis, parakeratosis, acanthosis underlined oral
leukoplakia in 4 cases and signs of hyperkeratosis,
orthokeratosis, the presence of Civatte bodies cells -
oral lichen planus in 3 cases. CONCLUSIONS. The characteristic aspects of white lesions of the oral
mucosa are based on a various pathogenetic mechanism and
are conditioned by keratinization disorders (leukoplakia,
oral lichen planus), the development of surface fungal
colonies (oral candidiasis), the presence of epithelial
necrosis (chemical lesions)
