SCREENING OF ANTIMICROBIAL ACTIVITY OF HERABAL EXTRACT OF MORINDA PUBESCENCEâ€, CHLORHEXIDINE & AMOXICILLIN AGAINST SALIVARY MICROFLORA OF MIXED DENTITION AGE GROUP.

Abstract

Objectives : In  this  study  the  Antimicrobial  activity  of  active Morinda Pubescenceâ€in  acetone  extracts  were  compared with  Chlorhexidine  and  Amoxicillin  125mg  and  Amoxicillin  250mg  against  human  salivary  microflora  at  different  concentrations. Method : The  antimicrobial  activity  was  assisted  by  measuring  the  inhibition  zones  by well  diffusion  method.  Saliva  was  collected  from  children  of  age  group  6-12  years  having DMFT  value  four  or  above  four.  Ten  salivary  samples  were  tested  for  antimicrobial  property  to  determine  the  Minimum  Inhibition  Concentration  in  order  to  increase  the  reliability  and  precision  of  the  study. Result: This study compares antimicrobial activity of Morinda Pubescenceâ€with  0.2percent  chlorhexidine and Amoxicillin 125mg and Amoxicillin 250mg. The zone of inhibition are measured by excluding the diameter of well. These zones of inhibition are directly proportional to the concentration. Conclusion : The  results  confirmed  the  antimicrobial  potential  of  Morinda Pubescenceâ€plant  at  different  concentrations  in  acetone  extracts  are  comparable  with  chlorhexidine  and Amoxicillin  and  can  be  used  as  preventive  and  therapeutic  measure  in  dentistry