ObjectiveTo evaluate the anti obesity effect of extract of Convolvulus pluricaulis in mice feed withcafeteria diet   MethodsObesity was induced in mice by feeding them a  daily for fourty one days in addition to normaldiet. Body weight and food intake was measured initially and then every week thereafter.On day fourty onefourty one serum biochemical parameter were measured and animal were sacrificedusing overdose of ether. The liver kidney fourty one heart and spleen were removed and weighedimmediately.Results may leads to obesity in mice however standard Sibutramine. Treatment with extractsof Convolvulus pluricaulis caused changes in the blood parameter including decease levelsof total cholesterol  TC fourty one low density lipoprotein cholesterol LDL C and TG but increasedhigh density lipoprotein cholesterolConclusionMethanolic extract of Convolvulus pluricaulis is a potential source of anti obesityphytomedicine.Keywords  Antiobesityfourty one Convolvulus pluricaulisfourty one Shankhpushpifourty one Obesityfourty one Phytomedicine.   Â
