This study investigated the blood and serum biochemistry following peritoneum sutured and not sutured techniques of laparotomy sutures in omentopexed WAD goats. Twentyfive male WAD goats were randomly divided into 5 groups (A – E). In group A, peritoneum was not sutured, while in group B, the peritoneum was sutured alongside with muscle layers. In groups C and D, omentopexy was performed and the laparotomy sutured as in groups B and A, respectively while, group E was the normal control. There was a significant (p<0.05) decrease in mean packed cell volume (PCV) (%) and red blood cell (RBC) (x106ìl) counts in all the surgery groups (A, B, C and D) but persisted only in group D till the end of the study - post surgery day (PSD) (day 14) when compared to the control group (E). There was a significant (p<0.05) increase in mean total WBC(x103/µl), neutrophil (x103/µl) and lymphocyte (x103/µl) counts in all the surgery groups but persisted only in group D to PSD, when compared to pre-surgery values (PSV) (day 0). The increases in mean total protein (g/dl) and mean albumin (g/dl) in groups A and B were significant (p<0.05) in group B goats only on PSD 2 while the significant (p<0.05) decreases in these values in group C (peritoneum sutured with omentopexy) and D (peritoneum not sutured with omentopexy) were significant (p<0.05) only in goats in group D from 10 to 14 PSD, when compared to PSV. The significant (p<0.05) increase in mean blood urea nitrogen (BUN) (mg/dl) in groups A and B persisted till the end of the study, while the significant (p<0.05) increase in mean BUN of goats in groups C and D, creatinine (mg/dl) and serum AST (iµ/dl) of goats in all the surgery groups returned to the PSV within the period of the study.Keywords: Suture techniques, Biochemical, Haematological changes, West African dwarf goat