Management of insect pests of cocoa (Theobroma cacao L.) using insecticides began in 1950 and has since gone through various programmes with concomitant challenges and successes. Presently Imidacloprid (Confidor®), Bifenthrin (Akatemaster®) and Thiamethoxam (Actara®)are recommended by Ghana Cocoa Board (COCOBOD) for the management of insect pests. A survey was conducted in the Ashanti, Eastern, Volta and Western Regions of Ghana using questionnaires and farm visits of 147 cocoa farmers’ fields to gather information on the characteristics of the farmers and insecticide handling and use by respondents. The survey showed that males dominated cocoa farming (72.7%) and most of them aged between 50 and 60 years. About 44% have had basic education whilst 37.5% of them belonged to farmer based organizations. About 52.8% of the farmers own motorized mistblower but 47.2% of the farmers use knapsack in the absence of a mistblower. About 44.8% do their own spray application whereas 55.2% hire labour. About 60.9% of the population across the regions read the label on the insecticides before application. A few (31.6 %) of the respondents put on the full personal protective costume during insecticide application and 21.9% do not use any protection. There was a positive correlation between farmers’ membership of farmer-based organisation and the costume-wearing farmers in the Ashanti, Eastern and Volta Regions and it was significant in the Ashanti region. It isrecommended that training and monitoring programmes be organized for farmers on the need to handle pesticides properly for personal and environmental safety and consumer benefit.Keywords: Insecticides; pest management; cocoa farmers; safet