Click on the link to view the book reviews.SAMJ 45(6

Terasaki, PI

English

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170 S.-A. MEDIESE TYDSKRIF 13 Februarie 1971fhere is less than 1 chance in 10 000 of obtaining a resultas large as this by chance alone. The average number ofdays off work for a patient having EeT was 32 (32·30 ±1·71), whereas for' chlorimipramine it was only 9 days,i.e. (8·98 ± 1·10). A roughly linear relationship was foundbetween the number of treatments for patients on ECTand the number of days off work. This is not true whena patient is on chlorimipramine where the maximumnumber of days off work was 30. This may not, however,be due to the effect of treatment, but rather to the methodof application. A sequential control chart again showedTOTAL SCORES50a breakthrough at a preassigned significance level ofp = 0·001 in favour of chlorimipramine (Fig. 2).This mean difference between the total scores was sig-nificant at the 1% level of significance in favour ofchlorimipramine (Fig. 3).The equations of the lines for sequential analyses usedwere:Y, -8'5168 + 0·4997XY, +8'5168 + 0·4997Xfor X = 0 Y, -8·5168 Y, = + 8·5168]7 030 6·560 21·5 = 38·5No of pairsFig. 3. Total scores.40"' 30.....CL'-00 20z100ChlorimipraminebetterE.C.T. better50 60SUMMARY AND CONCLUSIONSThe difference between the proportion of patients in hospitalwho improved when treated with electroconvulsive therapv.conventional antidepressant drug therapy and intravenous in·fusion of chlorimipramine was statistically significant in favourof the last-mentioned treatment. Patients on chlorimipramineas a group needed fewer treatments and returiled to workmore rapidly than did their counterparts having electrocon·vulsive therapy. There were no side-effects other than con·fusion in patients having electroconvulsive therapy while severalon the infusion suffered from mild side-effects. One patientdeveloped congestive cardiac failure. This was thought to bedue to other causes but was assessed as being due to theinfusion.I should like to thank Dr M. Salmon, Medical Superinten·dent of Johannesburg Hospital, for facilities granted and forpermission to publish; Prof. L A. HUTSt and Drs E. W. Rayner.P. J. Fischer, and R. Garb for assistance and co-operation:the nursing sisters in the unit and the doctors who participatedin the research project; and Miss E. Getz of tile Departmentof Statistics, University of the Witwatersrand, for ~tatisticalanalyses of data and assistance in interpreting the res:::,:. I alsowish to thank Dr D. Jacobs, of Geigy South Africa (Pty) Ltd,for his assistance and for the supply of chlorimipramine.B.G.G.BOOK REVIEWSHISTOCOMPATIBILIlYHislOcornpatibililY Testing 1970. Ed. by P. I. Terasaki. Pp.658. Illustrated. Dan. Kr. 148,50. Copenhagen: Munksgaard.1970.This is a comprehensive report (658 pages) on the January1970 International Workshop and Conference on Histocom-patibility Testing held in Palm Springs and Los Angeles. Everyaspect of the subject is extensively dealt with, including thegenetics and serology of the HL-A system, histocompatibilitytesting in clinical transplantation, the chemical characterizationof the HL-A antigens, and an excellent section on serologicaland immunological techniques. This is the most extensive andup-to-date work in this field currently available.THORACIC CAREChest Tubes and Chest Bollles. By A. von Hippel, M.D.,F.A.C.S., FI.C.S. Pp. xv + 96. $7.00. Springfield, Ill.:Charles C. Thomas. 1969.One is frequently approached, especially by colleagues inoutlying districts, on the use of intrapleural drainage tubes.It seems that few doctors, even students of thoracic surgery,let alone nurses, understand the 'mysteries' of chest tubes andchest bottles. _The author of this monograph has been most successful inpresenting all the facets of sealed pleural drainage in a clearlyillustrated, simple but concise way which makes tbe readingpleasant and most informative.This manual is a truly worth-while guide for all tbose con-cerned with thoracic care. J.C.v.d.S.BOEKBESPREKINGSATLAS VAN DWARSSNITTEA Cross-Section Anatomy. Deur A. C. Eycleshymer, B.S.,Ph.D., M.D. en D. M. Schoemaker, B.S., M.D. Pp. xvi +215. GeIllustreer. R32.00. Londen en Durban: Butterworth.1970.Dit is 'n atlas en handleiding van makroskopiese dwarssnittedeur die menslike liggaam. Die eerste uitgawe het in 1911verskyn en die huidige is 'n historiese heruitgawe van hierdieklassieke werk met die oorspronklike illustrasies voortreflikgedoen deur Tom Jones. In die eerste hoofstuk word diehistoriese agtergrond, doelstelling, materiaal en metodes be-spreek. Die regionale dwarssnitte, kop en nek, toraks, abdomen,bekken, ingeslote vroulike bekken en 1edemate word toegeligmet bygaande verklarings in hoofstuk twee. Die derde hoofstukword gewy aan die topografie van organe. Daar word ook 'nbibliografie gegee van die vemaamste boeke en tydskrifte watgeraadpleeg is.T.M.LIVER DISEASELiver Disease. By A. Paton, M.D., F.R.C.P. Pp. vii + 185.lllustrated. £1.10.0. London: William Heinemann MedicalBooks. 1970.This book sets out to present liver disease in a succinct butrelatively superficial manner. Unfortunately its very abbrevia-tion makes it of limited value. It has the defect of merelywhetting the appetite while supplymg nothing like enoughinformation to give the student a real appreciation of tbeclinical problems in liver disease. Certain important areas aretreated far too sup~rficially. S.J.S.

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