We present the case of a 2-week-old male infant who presented with an asymptomatic liver mass and underwent surgical resection because of suspicion of malignancy after extensive radiological study with ultrasonography, computed tomography, and MRI. Pathological examination revealed a peripheral hepatic infarct with calcifications and a rim of peripheral organization suggestive of being at least 2 weeks old. This case reviews the scarce cases of hepatic infarct in newborns and highlights the fact that, although untreated perinatal hepatic infarction usually progresses to atrophy of the affected area with compensation by the unaffected liver, surgical resection remains an option in cases of complications or uncertain diagnosis
