Cyclohexenones Through Addition of Ethyl Acetoacetate to 3-Aryl-1-(thiophen-3-yl)prop-2-en-1-one Derivatives

Abstract

Chalcone derivatives 3a–i containing a thiophene ring were prepared by the condensation of 1-(thiophen-3-yl)ethanone with aromatic aldehydes in excellent yields. The Michael addition of ethyl acetoacetate 4 to chalcone derivatives 3a–i resulted in the formation of nine novel ethyl 6-aryl 4-(3-thienyl)cyclohex-3-en-2-one-1-carboxylate derivatives 6a–i.Keywords: Michael Addition, Ethyl Acetoacetate, Cyclohexenones, Cyclocondensatio

    Similar works