Anaemia is the most common nutritional deficiency in pregnant women which is more prevalent in developing than developed countries of the world. Pregnancy is considered as a pro-inflammatory condition and anaemia may modulate leukocytosis and inflammation during gestation. The objective of this study was to investigate changes in neutrophil-to-lymphocyte ratio (NLR) in anaemic pregnant women compare with nonanaemic pregnant women and to correlate such changes with a sensitive traditional marker of inflammation. Full blood count and high sensitive C-reactive protein (hsCRP) were determined in 522 anaemic pregnant women and 600 non-anaemic pregnant women on their first ante-natal visits to three hospitals in Ogun State, Nigeria. The full blood count was analyzed using Coulter counter cell dye auto-analyzer by Abott diagnostics (Wiesbaden, Germany) while hsCRP was assayed using reagents supplied by Abbot Diagnostics BV (Hoofddorp, Netherlands). The means total white blood count (p=0.044), neutrophil (p=0.031), lymphocyte (p=0.042), eosinophil (p=0.008),NLR (p<0.001) and hsCRP(p<0.001) were significantly higher in anaemic pregnant women than non-anaemic pregnant women. The mean levels of NLR and hsCRP significantly increased from mild anaemia, moderate anaemia to severe anaemia compared with levels in non-anaemic pregnant women. NLR correlated positively (r=0.128;p=0.005) with hsCRP in anaemic pregnant women. The NLR may be used in clinical setting in the assessment of inflammation in pregnant women.Key words: Anaemia, inflammation, neutrophil-to-lymphocyte ratio, pregnanc