CORE
🇺🇦
make metadata, not war
Services
Services overview
Explore all CORE services
Access to raw data
API
Dataset
FastSync
Content discovery
Recommender
Discovery
OAI identifiers
OAI Resolver
Managing content
Dashboard
Bespoke contracts
Consultancy services
Support us
Support us
Membership
Sponsorship
Community governance
Advisory Board
Board of supporters
Research network
About
About us
Our mission
Team
Blog
FAQs
Contact us
A systematic review of case reports of hepatic actinomycosis
Authors
Z. Chegini
M. Didehdar
+3 more
A. Khoshbayan
A. Shariati
S.P. Tabaeian
Publication date
1 January 2021
Publisher
'Springer Science and Business Media LLC'
Abstract
Background: Hepatic Actinomycosis (HA) is one of the infections that causes disorders in patients when diagnosed untimely and inappropriately. Methods: Case reports on HA in patients published between 2000 and April 2020 were gathered by carrying out a structured search through PubMed/Medline. Results: Through a survey of the Medline database, 130 studies were identified and then, 64 cases with HA were included in the final analysis. Asia had the largest share of cases with 37.5 (24 reports), followed by Europe and the Americas. Affected patients were predominantly males (64) and the overall mortality rate was 1 with only one male patient in his 50 s dying. Nearly all patients (92) were immunocompetent. However, in four patients, the use of immunosuppressive medication led to depression of the immune system. Most of the patients (80) experienced complications. In terms of the complications, the most frequent ones were previous history of abdominal surgery (32) and foreign bodies in the abdominopelvic region (20). Actinomyces israelii was the most common pathogen isolated from patients. Abdominal pain (66), fever (62), weight loss (48), night sweat, malaise, and anorexia (14) over about 3.1 months were the most frequently reported clinical symptoms. Extension to one or more surrounding organs was evident in 18 patients (28). Histopathologic examination confirmed infection in 67 of the patients and samples obtained from liver puncture biopsy (32) were most frequently used in diagnosis. Surgery or puncture drainage + anti-infection was the most common method to treat patients and penicillin, Amoxicillin, Doxycycline, and ampicillin were the most frequently used drugs to control infection. Conclusion: HA should be considered in patients with a subacute or chronic inflammatory process of the liver. With accurate and timely diagnosis of infection, extensive surgery can be prevented. © 2021, The Author(s)
Similar works
Full text
Open in the Core reader
Download PDF
Available Versions
eprints Iran University of Medical Sciences
See this paper in CORE
Go to the repository landing page
Download from data provider
oai:eprints.iums.ac.ir:38862
Last time updated on 11/10/2021