Puyalasa (Acute dacryocystitis) is an acute suppurative inflammation of lacrimal sac characterized by painful swelling in the region of sac associated with epiphora, fever and Malaise. Puyalasa, is one of the Sandhigata Roga which includes swelling in Kaninika sandhi, which later on undergoes suppuration causing thick purulent discharge. The present study was planned to assess the efficacy of Jalaukavacharana and Shadanga Guggulu in Amavastha and Pachyamanavastha of Puyalasa. Total 60 patients of Puyalasa (Amaavastha and Pachyamanavastha) were randomly selected and grouped into Group A, B and C with 20 patients in each group. The patients of Group-A received Jalaukavacharana as a line of treatment, patients of Group-B received Shadanga Guggulu and Patients of Group-C received both Jalaukavacharana and Shadanga Guggula. In all the three groups the Group-C in which both Jalaukavacharana and Shadanga Guggulu were included is very effective after treatment of 15days and statistically significant in reducing Shopha, Savedena, and Sarambha
