Human semen serves as fluids medium in which sperm cells are dispersed and swim within. Semen contains about 90% water along with proteins that include Immunoglobulin-A (IgA), Haptoglobin, fructose sugar, other dissolved substances and electrolyte. Apart from preserving the sperm cells, semen may carry certain immunological feature as part of its protective functions. From a male partner in coital activity, semen’s cellular component and proteins deposited into the vagina do not antigenically qualify as ‘self’. This is a study to determine a possible agglutination resistant effect of semen on various types of ABO and Rhesus blood group members or agglutination enhancing effect of the same ABO and Rhesus group members. Keywords: Rhesus, ABO, Blood Group Agglutination Semen Haptoglobin. DOI: 10.7176/JMPB/71-01 Publication date:June 30th 2021
