Background ; Health related quality of life (HRQOL) is studied widely, after weight loss by insertion of BioEnterics Intragastric Balloon,but quality of life (QOL) not related to the health of the patients is not studied after body weight loss by any means on wide scale. Aim: To evaluate extend of body weight loss in general and particularly after BIB insertion or Atkins diet and changes of quality of life in the obese patients after body weight loss. Patients, materials and methods: Prospective study, from a total of 180 patients, 80 of them selected over a period of 4 years, included patients divided in to two comparable groups, first treated with insertion of Bioenterics intragastric balloon and the second subjected to modified Atkins diet for 6 months. Each patient in either group followed up monthly for 18 months ,the patients were interviewed before the star and after completion of the treatments to fill the quality of life questionnaire. The collecting data were analyzed using the IBM SPSS ( statistical package for social science) statistics version 21. Results: Two comparable groups of obese patients were studied, each group consists of 40 female patients, mean age in group A was 27years (20-39 years) with mean body weight 90 kg (80-100) and mean BMI 36(31-39.9) who were treated with insertion of BIB. While mean age in group B was 29 years (20-39 years) with mean body weight 91 kg (80-102) and mean BMI 36.5 (31-39.9). Statistically important changes occurred in the quality of life of the patients after either method of treatments to different degrees (p value 0.005917) Conclusion: BioEnterics Intragastric Balloon reduces more weight and BMI in 6 months in comparison to modified Atkins diet, and results in statistically significant improvement of most aspects of quality of life. Keywords: obesity, quality of life, loss of weight, BioEnterics Intragastric Balloon, Atkins diet. BioEnterics Intragastric Balloo
