Hyperemesis Gravidarum and Helicobacter Pylori Stool Antigen Positivity

Abstract

OBJECTIVE: Nausea and vomiting of pregnancy (NVP) is a common problem for patients during first trimester. The causes of this problem are multifactorial. Recent studies have shown association between hyperemesis gravidarum (HG) and Helicobacter Pylori infection. We aim to evaluate this association. STUDY DESIGN: Thirty-seven patients who were diagnosed HG were compared with 40 asymptomatic pregnant women. Direct stool antigen testing with using ELİSA (Enzyme Linked İmmunosorbent Assay) was performed. RESULT: Helicobacter pylori stool antigen was detected in 11 (27.5%) patients in control group. in HG group Helicobacter pylori stool antigen was detected in 8 (21.6%) patients. there were no statistically significant difference. CONCLUSION: Our study was unable to confirm association between HG and H. pylori. For elimination of genetic factors different population is should be evaluated