Background & Objectives: Ecologic conditions affect
production of effective pharmaceutical products. We evaluate the effect of
ecologic conditions on antibacterial effects of herbal plants in Fars. Materials & Methods: We collected eight plant species
including Trachyspermum copticum, Withania somnifera, Laurus nobilis, Carum carvi, Thymus, Rosemary, Zataria multiflora, and Lavandula in Fasa and
Sepidan.. Their antibacterial effects were studied by disk diffusion method,
well assay method, and Minimum Inhibitory Concentration (MIC). Ecological and
weather conditions were derived from internet. Results: Comparing with standard antibacterial
indexes the following results were achieved. Fasa herbs including Trachyspermum copticum, Zataria multiflora, Laurus nobilis, and Rosemary had the most effect on Staphylococcus aureus, while Carum
carvi had the least effect. This effect in Sepidan herbs was the most in
Trachyspermum copticum, Zataria multiflora, and Rosemary, while Carum carvi had
the least effect. Surveying the effects against E.coli among Fasa herbs,
Zataria multiflora had the most and Carum carvi and Lavandula had the least effects.
On the other hand, among Sepidan herbs, Trachyspermum had the highest and Carum
carvi, Lavandula, and Laurus nobilis had the lowest effects on E.coli.
Antibacterial effects of Fasa herbs against Pseudomonas aeruginosa was the most
in Zataria multiflora and Thymus and the least in Carum carvi. In Sepidan
herbs, it was the highest in Zataria multiflora and the lowest in Carum carvi.Conclusion: Considering the differences in
antibacterial effects of the herbs in two ecologic conditions, we suggest other
researchers to pay attention to the mentioned effects in their studies
