Antibiotic Resistance Pattern of Staphylococcus aureus Strains Isolated from Personnel of Jahrom Hospitals in 2012

Abstract

Abstract Background and aim: In recent decades, inappropriate antibiotic therapy has been led to the emergence of strains resistant to methicillin and vancomycin. Since the main source of infection and transmission of Staphylococcus aureus is by hospital staff, the aim of this study was to determine the antimicrobial susceptibility of S.aureus strains isolated from hospital staff of Jahrom. Undo edits Methods: In this cross - sectional study, 397 of the anterior nasal samples of medical personnel and hospital services were collected by swab. The identification of S.aureus was determined by biochemical tests and microbiology, and the antibiotic resistances of isolates were determined by disk diffusion method for 13 antibiotics. In this method, the inhibition zone for methicillin-resistant strains was ≤ 10 mm the minimum inhibitory concentrations (MIC) against antibiotic vancomycin, ticoplanin, linezolid and synercid were determined by E-test method. Results: In the present study, 11.3% of personals carried S. aureus in the nose. Among them, 90% were health care workers and 10% were health service workers. The most sensitivity was observed resistance to Ciprofloxacin, rifampin, linezolid and synercid (91.1%), but the lowest sensitivity was to penicillin (4.7%). of 9 MRSA strains, 1 strain was resistance to vancomycin and 2 strains were resistant to teicoplanin and linezolid. Conclusion: Because of S. aureus strains isolated from hospital staffs were resistant to most common antibiotics, identification and treatment of health care and health service workers can prevent nosocomial infections. Key words: Staphylococcu aureus carriers, hospital personnel, antibiotic resistance