2-Cyanoethylzinc iodide: A new reagent with reactivity umpolung

Abstract

2-Cyanoethylzinc iodide 1 generated in over 90% yield from 3-iodopropionitrile and zinc in THF can be transmetallated to the copper and titanium derivatives 3 and 4 which react in good yields, respectively, with acyl chlorides, enones, allylic halides and benzaldehyde.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/27612/1/0000656.pd

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