Severe panuveitis in neuro-Behçet’s disease in Malaysia: a case series

Abstract

Khairuddin Othman,1 Ahmad Tajudin Liza-Sharmini,1 Mohtar Ibrahim,1 John Tharakan,2 Ryoji Yanai,3 Embong Zunaina1 1Department of Ophthalmology, 2Department of Neurosciences, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia; 3Department of Ophthalmology, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan Abstract: Behçet’s disease (BD) is a multisystemic disease that is very rare in Malaysia. About 5% of patients develop central nervous system involvement, termed neuro-Behçet’s. Neuro-Behçet’s is one of the most serious causes of long-term morbidity and mortality. We report two cases of neuro-Behçet’s associated with uveitis (ocular BD) highlighting the clinical presentation, diagnostic measurement, and therapeutic management of these cases.Keywords: Behçet’s disease, Behçet’s syndrome, parenchymal neuro-Behçet’s, uveiti