Cytotoxicity, Platelet Aggregation Inhibitory and Antioxidant Activity of Curcuma amada Roxb. Extracts

Abstract

Mango ginger (Curcuma amada Roxb.) is a unique spice having morphological resemblance to ginger but imparts raw mango flavour. The sequential extraction of mango ginger rhizome powder was carried out using hexane, chloroform, ethyl acetate, acetone, methanol and water. The phenolic content was the highest in methanol extract, followed by acetone, ethyl acetate and water extracts. Among these, chloroform extract exhibited high lipid peroxidation inhibitory activity and metal chelating activity, whereas ethyl acetate extract showed high DPPH radical scavenging activity and superoxide radical scavenging activity. Mango ginger extracts also showed potential platelet aggregation inhibitory activity and cytotoxicity properties