The study is targeting to examine the effects of 2001 financial crisis on the shares included in the lowest-risk portfolios of Istanbul Stock Exchange. To this end; monthly returns data of all shares traded in Istanbul Stock Exchange between 2000:11-2002:09 term, are evaluated. While portfolio selection is carried out via Markowitz Model, the effects of 2001 financal crisis are examined whereby ratio analysis. The findings display that the firms examined have benefited from the positive impact of exporting, furthermore, the amounts of short term debts are increased. Besides, both stock retention and receivable collection periods of the mentioned firms are decreased