We prepare high-filling two-component arrays of up to fifty fermionic atoms
in optical tweezers, with the atoms in the ground motional state of each
tweezer. Using a stroboscopic technique, we configure the arrays in various
two-dimensional geometries with negligible Floquet heating. Full spin- and
density-resolved readout of individual sites allows us to post-select near-zero
entropy initial states for fermionic quantum simulation. We prepare a
correlated state in a two-by-two tunnel-coupled Hubbard plaquette,
demonstrating all the building blocks for realizing a programmable fermionic
quantum simulator