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Previous issue date: 2011Fundação Oswaldo Cruz. Instituto Nacional da Saúde da Mulher e da Criança Fernandes Figueira. Departamento de Genética Médica. Rio de Janeiro, RJ, Brasil.Instituto Nacional do Câncer. Genética Médica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional da Saúde da Mulher e da Criança Fernandes Figueira. Departamento de Genética Médica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional da Saúde da Mulher e da Criança Fernandes Figueira. Departamento de Genética Médica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional da Saúde da Mulher e da Criança Fernandes Figueira. Departamento de Genética Médica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional da Saúde da Mulher e da Criança Fernandes Figueira. Departamento de Genética Médica. Rio de Janeiro, RJ, Brasil.Objectives: investigation of the locomotion process in patients
with osteogenesis imperfecta (OI), and the factors that influence
it, with special attention to clinical aspects relating to motor
rehabilitation. Methods: a retrospective, cross-sectional study
was carried out at the physical therapy outpatient clinic of the
Instituto Fernandes Figueira. All patients with a clinical diagnosis
of OI were included. Patients with other diseases, and those
aged under two years, old were excluded. Epi-Info version 3.4
was used to construct the database, and SPSS version 15 for
the statistical analysis. Results: The odds-ratio was used to measure
the association between independent walking and clinical
characteristics, adopting a level of significance of 5% for the
analysis. Results: 69 patients were included. Of these, 43.5%
were classified as OI type I; 37.7% as type III and 18.8% as type
IV. 76.8% presented long bone deformities. A negative association
was observed between hypotonia, number of fractures, and
independent walking. A positive association was observed between
independent walking and OI type I. Conclusions: physical
therapy, as a complementary approach to orthopedics, and the
administration of medications of the biophosphonates class, are
of fundamental importance for the rehabilitation of motor capacity
of individuals with OI. Level of Evidence, cross sectional
