Liberal vs. restrictive strategy of red blood cells transfusion in elderly: analysis of randomized

Abstract

Objetivo: Comparar a evolução clínica de pacientes críticos idosos (>= 60 anos) com pacientes mais jovens (= 60 years-old) occurred in 63.3% of patients in the liberal strategy group and in 69.4% of patients in the restrictive strategy group (p=0.123). However, in the older patients, cardiogenic shock was more frequent in patients in the restrictive transfusion group (14.8% vs 6%, p=0.001). Conclusions: Although there was no difference between groups regarding the primary outcome, a restrictive transfusion strategy was associated with an increased rate of cardiogenic shock in elderly critical patients compared with a more liberal strategy. Cardiovascular risk of anemia may be more harmful than the risk of blood transfusion in older patient

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