The effect of neuroloptics. Carbamacepine and hensmliacepines in treatment of 8.3 patients with acute mania was studied. According to drug types. Patients were divided into 5 groups:"n1) lithium combined with ilubupridol. "n2) Lithium combined with one plxenoshiacine "n3) Lithium combined with two phenothiazines. "n4) Lithium combined with cubumazepine and "n5) Lithium combined with benzxliazepines "nNo singnificunt differences in duration of treatment among the groups were found. According to increased risk of extrapyramidol symptoms in treatment with neuroloptics, carbamazepine or benzxliazepines are preferred in treatment of acute mania as safer comedicutions. &nbsp