In order to increase radio-sensitivity of human lung adenocarcinoma NCI-H1568
cells, targeted therapy drug, erlotinib was used. The impact of radiation and
erlotinib on cell behaviour was analyzed using three biological endpoints.
Irradiations with γ-rays resulted in reduction of cell survival, viability and
proliferation. Erlotinib significantly inhibited cell growth and proliferation
capacity. Combined treatments with radiation and erlotinib showed high level of
reduction of cell viability and proliferation. Preliminary data encourage further
investigations of mechanisms underlying the radiation responses enhanced by
erlotinib.Physical chemistry 2012 : 11th international conference on fundamental and applied aspects of physical chemistry; Belgrade (Serbia); 24-28 September 201
