'Prof. Marin Drinov Publishing House of BAS (Bulgarian Academy of Sciences)'
Abstract
In this paper, a genetic algorithm is used to determine the Mean Corpuscular Volume (MCV) as the optimal decision-making criterion for anemia caused by iron deficiency based on the diagnostic test of patients with such anemia. On the premise of attaining maximum sensitivity and specificity for the cost, this paper studies the impact of the cost ratio of the optimal decision-making criteria and compares the mathematical derivation and binominal model method, so as to discuss the application of the optimal diagnostic criteria in the genetic algorithm and provide a practical study method for the diagnostic test
