Preparative purification of ochratoxin a by liquid-liquid chromatography

Abstract

Ochratoxin A is an important mycotoxin, produced by different Aspergillus and Penicillium species hence there are strict regulations on its level in foods and feeds. Qualitative and quantitative measurements of this compound require relatively high amounts of pure ochratoxin A as a standard. This large amount of pure compound can be obtained by purifying the fermentation medium of the producing microorganisms. Liquid-liquid chromatography (LLC) seems to be a suitable method, which is becoming more common in the purification of natural compounds

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