Vienna City is one of the most attractive cities in Europe and according to different rankings [1], [2]it is placed on the top ten in the list of cities with best living conditions, excellent education, infrastructure and good urban planning. This is the result of a systematic approach of the local government, companies, universities and public in the development and modernization of the city. Since 2000 the city has known a growth in different areas (number of researchers, number of patents, joint programs for the popularization of science etc.) and evolved into a network point not only for business but also for research and innovation. In this paper we investigate the strategy of Vienna City regarding research and development and the extensive and complex role of universities in the city