Paraparesia espástica tropical/mielopatia associada ao HTLV-1: relato de dois casos com manifestações dermatológicas em familiares de doador de sangue HTLV-1 positivo assintomático no Hemocentro do Amazonas - Hemoam Tropical spastic paraparesis/myelopathy associated with HTLV-1: report of two related cases with dermatological involvement

Abstract

Dois casos de paraparesia espástica tropical / mielopatia associada ao HTLV-1 (HAM/TSP) foram diagnosticados no Hemocentro do Amazonas - Hemoam, em familiares de doador de sangue soropositivo para o HTLV-1 assintomático. Aqui descrevemos a investigação familiar, as características clínicas dos casos e as manifestações dermatológicas associadas.<br>Herein we report on two cases of tropical spastic paraparesis / myelopathy associated with HTLV-1 (HAM/TSP) diagnosed in relatives of a blood donor found positive for HTLV-1 at serologic screening. The donor himself was asymptomatic. Family studies, the clinical characteristics of the cases and the associated dermatologic manifestations are reported