Subgingival Human Cytomegalovirus and Epstein Barr Virus in Patients with Aggressive Periodontitis in Ahwaz, Iran

Abstract

Objective: Assessment of subgingival human cytomegalovirus (HCMV) and Epstein Barr virus (EBV-1) in subjects with aggressive periodontitis.Materials and Methods: Samples were obtained from plaques formed in subgingival regions of 26 aggressive periodontitis patients. All specimens were submitted to polymerase chain reaction in order to detect HCMV and EBV-1.Results: HCMV and EBV-1 were observed in 27% and 25% of the participants respectively.Coinfection with both viruses was found in 52% of the patients.Conclusion: Within the limitations of the present study, it can be suggested that HCMV and EBV-1 in subgingival plaques may be associated with aggressive periodontitis. Additionally,concomitant occurrence of these viruses may negatively affect the wellbeing ofperiodontal tissues