[EN] In the present work, we analyze the influence of the designer's choice of values for the human metabolic index (met) and insulation by clothing (clo) that can be selected within the ISO 7730 for the calculation of the energy demand of buildings. To this aim, we first numerically modeled, using TRNSYS, two buildings in different countries and climatologies. Then, we consistently validated our simulations by predicting indoor temperatures and comparing them with measured data. After that, the energy demand of both buildings was obtained. Subsequently, the variability of the set-point temperature concerning the choice of clo and met, within limits prescribed in ISO 7730, was analyzed using a Monte Carlo method. This variability of the interior comfort conditions has been finally used in the numerical model previously validated, to calculate the changes in the energy demand of the two buildings. Therefore, this work demonstrated that the diversity of possibilities offered by ISO 7730 for the choice of clo and met results, depending on the values chosen by the designer, in significant differences in indoor comfort conditions, leading to non-negligible changes in the calculations of energy consumption, especially in the case of big buildings.This work was partially funded by grants OHMERA MAT2017-86453-R, FIS2017-83762-P and ENE2015-71333-R from MINECO (Spain). R. Robledo and M. Hernandez were supported by CONACYT grants 298503 and 296471, respectively. We also thanks to supporting given by the project number INFRA-187906 from the Mexican National Council of Science and Technology-CONACYT.Robledo-Fava, R.; Hernández-Luna, MC.; Fernández De Córdoba, P.; Michinel, H.; Zaragoza, S.; Castillo-Guzman, A.; Selvas-Aguilar, R. (2019). Analysis of the Influence Subjective Human Parameters in the Calculation of Thermal Comfort and Energy Consumption of Buildings. 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