In Australia, out-of-hospital cardiac arrest (OHCA) affects an estimated 26,000 people each year; with a mortality rate of approximately 88%. A structured approach to OHCA management as defined by the 'Chain of Survival' is critical to high-quality patient outcomes. The aim of this thesis was to strengthen the post-resuscitation care link in the Chain of Survival by examining the effect of in-hospital factors on survival and neurological outcome after OHCA